科研文章 - 上海力山生物医药有限公司

2021-07 Gastroenterology (IF = 25.1)

Bacterial swarmers enriched during intestinal stress ameliorate damage

2021-04 eLife (IF = 6.4)

Confinement discerns swarmers from planktonic bacteria

2025-05 Gut Microbes (IF = 11.0)

Deep learning-based detection of bacterial swarm motion using a single image

2019-06 Biophysical Journal (IF = 3.1)

Orbiting of flagellated bacteria within a thin fluid film around micrometer-sized particles

2024-06 STAR Protocols (IF = 1.3)

Protocol for isolating single species of bacteria with swarming ability from human feces

2021-09 Bio-Protocol (IF = 1.1)

An inexpensive imaging platform to record and quantitate bacterial swarming

2015-01 Cell (IF = 42.5）

A Qrr non-coding RNA deploys four different regulatory mechanisms to optimize quorum-sensing dynamics

2020-01 PNAS (IF = 9.1)

Identifying determinants of bacterial fitness in a model of human gut microbial succession

2009-09 PNAS (IF = 9.1)

Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage

2013-07 The EMBO Journal (IF = 8.3)

Functional determinants of the quorum-sensing non-coding RNAs and their roles in target regulation

2015-11 Chemical Science (IF = 7.4)

Time-resolved proteomic analysis of quorum sensing in Vibrio harveyi

2024-06 Journal of Microbiology (IF = 2.6)

Identification of avaC from Human Gut Microbial Isolates that Converts 5AVA to 2-Piperidone

2023-09 Computers in Biology and Medicine (IF = 6.3)

RDKG-115: Assisting drug repurposing and discovery for rare diseases by trimodal knowledge graph embedding

2022-02 Bioinformatics (IF = 5.4)

Multimodal reasoning based on knowledge graph embedding for specific diseases

2023-06 Bioinformatics (IF = 5.4)

MDTips: A multimodal-data-based drug–target interaction prediction system fusing knowledge, gene expression profile, and structural data

2024-10 BMC Biology (IF = 4.5)

TransCDR: Deep learning model for enhancing the generalizability of drug activity prediction through transfer learning and multimodal data fusion

2024-08 Bioengineering (IF = 3.7)

Constructing a Clinical Patient Similarity Network of Gastric Cancer

2021-12 Genes (IF = 2.8)

Attention-based deep multiple-instance learning for classifying circular RNA and other long non-coding RNA

2022-10 International Journal of Molecular Sciences (IF = 4.9）

MicroRNA-150 (miR-150) and Diabetic Retinopathy: Is miR-150 Only a Biomarker or Does It Contribute to Disease Progression?

2021-10 Journal of Cellular and Molecular Medicine (IF = 4.2）

MicroRNA-150 and its target ETS-domain transcription factor 1 contribute to inflammation in diabetic photoreceptors

2020-09 BMJ Open Diabetes Research & Care (IF = 4.1）

Decreased miR-150 in obesity-associated type 2 diabetic mice increases intraocular inflammation and exacerbates retinal dysfunction

2021-09 Biomedicines (IF = 3.9）

Decreased MicroRNA-150 Exacerbates Neuronal Apoptosis in the Diabetic Retina

2019-04 Journal of Diabetes Research (IF = 3.4）

Melatonin Affects Mitochondrial Fission/Fusion Dynamics in the Diabetic Retina

2019-08 Nature (IF = 48.5)

Controlling organization and forces in active matter through optically defined boundaries

2018-02 PNAS (IF = 9.1)

Changes in the flagellar bundling time account for variations in swimming behavior of flagellated bacteria in viscous media

2021-08 Communications Physics (IF = 5.8)

Persistent fluid flows defined by active matter boundaries

2020-07 Physical Review Fluids (IF = 2.8)

Effects of shear-thinning viscosity and viscoelastic stresses on flagellated bacteria motility

2025-09 Redox Biology (IF = 11.9)

Discovery of a novel chalcone-derived covalent Keap1 binder for mitigating cisplatin-induced mitochondrial dysfunction and nephrotoxicity

2025-08 Acta Pharmaceutica Sinica B (IF = 14.6)

High-efficient discovering the potent anti-Notum agents from herbal medicines for combating glucocorticoid-induced osteoporosis

2025-03 Small (IF = 12.1)

Functional imaging of CYP3A4 at multiple dimensions using an AI-driven high performance fluorogenic substrate

2025-01 Acta Pharmaceutica Sinica B (IF = 14.6)

Discovery of a novel AhR–CYP1A1 axis activator for mitigating inflammatory diseases using an in situ functional imaging assay

2020-05 Nucleic Acids Research (IF = 13.1)

Nono deficiency compromises TET1 chromatin association and impedes neuronal differentiation of mouse embryonic stem cells

2020-02 Protein & Cell (IF = 12.8)

DNMT3A reads and connects histone H3K36me2 to DNA methylation

2019-08 Science Advances (IF = 12.5)

Epigenetic signatures of methylated DNA cytosine in Alzheimer’s disease

2021-03 Clinical and Translational Medicine (IF = 6.8)

Quantitative acetylome analysis reveals histone modifications that may predict prognosis in hepatitis B‐related hepatocellular carcinoma

2015-09 Nature (IF = 48.5)

Neutrophil ageing is regulated by the microbiome

2022-02 Cell Stem Cell (IF = 20.4)

The microbiota regulates hematopoietic stem cell fate decisions by controlling iron availability in bone marrow

2020-08 Immunity (IF = 26.3)

The gut microbiome regulates psychological stress-induced inflammation

2019-05 Blood (IF = 23.1)

Cross talk between neutrophils and the microbiota